CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) is a revolutionary gene-editing technology derived from a natural bacterial immune system.
Key points:
Uses a guide RNA to direct the Cas9 protein to cut specific DNA sequences.
Allows precise insertion, deletion, or modification of genes.
Applications: curing genetic diseases, improving crops, biomedical research.
Nobel Prize in Chemistry (2020) awarded to Doudna & Charpentier for its discovery.
It’s faster, cheaper, and more accurate than older gene-editing methods.
Genetic Disorder
Genetic Diseases Treatable with Gene Editing and Key Case Studies (As of May 2025) Gene editing technologies, particularly CRISPR-Cas9, have enabled precise interventions for monogenic disorders while making breakthroughs in polygenic diseases, mitochondrial disorders, and rare conditions. Below is …
Cancer
Can Gene Editing Eradicate Cancer? A Multidimensional Analysis Gene editing technologies—particularly CRISPR-Cas9 and its derivatives—show revolutionary potential in cancer treatment. However, whether they can truly "eradicate cancer" requires a comprehensive analysis across three dimensions: techno…
Genetic disease
Latest Applications of Gene Editing in Genetic Disease Treatment (As of May 2025) Gene editing technologies are revolutionizing the treatment of genetic disorders. Below is a systematic review of recent advancements across four dimensions: technical breakthroughs, clinical applications, multi-system…
Coronary Heart Disease (CHD)
Selecting the Optimal Treatment for Coronary Artery Disease and the Importance of Daily Health Management (As of May 2025) I. Strategies for Choosing CAD Treatments Effective management of coronary artery disease (CAD) requires a personalized approach that integrates disease severity, patient-specif…
Coronary Heart Disease (CHD)
Traditional Treatments and Best Practices for Coronary Artery Disease (CAD) (As of May 2025) The traditional treatment system for coronary artery disease (CAD) encompasses pharmacological therapies, surgical interventions, minimally invasive procedures, cardiac rehabilitation, and traditional Chines…
Coronary Heart Disease (CHD)
Gene Editing Technologies for Coronary Artery Disease (CAD) Treatment (As of May 2025) The treatment of coronary artery disease (CAD) has entered an era of precision intervention through gene editing. Below is a systematic review of current gene-editing technologies applied to CAD, covering mechanis…
Coronary Heart Disease (CHD)
Innovative Strategies Combining Surgical and Gene-Editing Therapies for Coronary Heart Disease (As of May 2025) The treatment of coronary artery disease (CAD) has evolved from traditional surgical interventions to a precision medicine era. Recent advances in combining gene-editing technologies with …
Common Diseases
Potential Risks of Gene Editing in Coronary Heart Disease (As of May 2025) Gene editing technologies (e.g., CRISPR-Cas9, base editing) offer revolutionary strategies for treating coronary heart disease (CHD), but their clinical application faces multidimensional risks. Below is an analysis spanning …
Common Diseases
Comparative Analysis of Immunotherapy vs. Gene Editing Therapy (As of May 2025) 1. Core Mechanisms and Targets Immunotherapy Principle: Activates or enhances the patient’s immune system to recognize and kill tumor cells, primarily through engineered T cells (e.g., CAR-T) or immune checkpoint inhibit…
Common Diseases
Latest Advances in Gene Technology for Common Disease Treatment (As of May 2025) Breakthroughs in CRISPR-Cas9, base editing, and mRNA delivery have propelled gene technology from labs to clinics, revolutionizing treatments for cancer, cardiovascular diseases, genetic disorders, and more. Below are k…