CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) is a revolutionary gene-editing technology derived from a natural bacterial immune system.
Key points:
Uses a guide RNA to direct the Cas9 protein to cut specific DNA sequences.
Allows precise insertion, deletion, or modification of genes.
Applications: curing genetic diseases, improving crops, biomedical research.
Nobel Prize in Chemistry (2020) awarded to Doudna & Charpentier for its discovery.
It’s faster, cheaper, and more accurate than older gene-editing methods.
Gene Technology: Breakthroughs in Longevity Gene Discovery Recent advances in gene technology have accelerated the exploration of longevity genes, revealing molecular mechanisms of aging and identifying potential targets for anti-aging therapies. Through interdisciplinary approaches—including evolut…
Gene Therapy for Alzheimer’s Disease: Breakthroughs and Challenges (As of May 2025) I. Core Therapeutic Strategies Alzheimer’s disease (AD) gene therapy focuses on modulating genetic risk factors, repairing neuronal damage, and inhibiting pathological protein accumulation (e.g., β-amyloid [Aβ] and t…
Genetic Diseases in Active Gene Editing Clinical Trials and Progress (As of May 2025, based on global clinical trial data) I. Hematologic Disorders 1. Sickle Cell Disease (SCD) & β-Thalassemia Candidate Therapies: exa-cel (CTX001): Co-developed by CRISPR Therapeutics and Vertex, this therapy act…
Genetic Diseases Treatable with Gene Editing and Key Case Studies (As of May 2025) Gene editing technologies, particularly CRISPR-Cas9, have enabled precise interventions for monogenic disorders while making breakthroughs in polygenic diseases, mitochondrial disorders, and rare conditions. Below is …
Can Gene Editing Eradicate Cancer? A Multidimensional Analysis Gene editing technologies—particularly CRISPR-Cas9 and its derivatives—show revolutionary potential in cancer treatment. However, whether they can truly "eradicate cancer" requires a comprehensive analysis across three dimensions: techno…
Latest Applications of Gene Editing in Genetic Disease Treatment (As of May 2025) Gene editing technologies are revolutionizing the treatment of genetic disorders. Below is a systematic review of recent advancements across four dimensions: technical breakthroughs, clinical applications, multi-system…
Selecting the Optimal Treatment for Coronary Artery Disease and the Importance of Daily Health Management (As of May 2025) I. Strategies for Choosing CAD Treatments Effective management of coronary artery disease (CAD) requires a personalized approach that integrates disease severity, patient-specif…
Traditional Treatments and Best Practices for Coronary Artery Disease (CAD) (As of May 2025) The traditional treatment system for coronary artery disease (CAD) encompasses pharmacological therapies, surgical interventions, minimally invasive procedures, cardiac rehabilitation, and traditional Chines…
Gene Editing Technologies for Coronary Artery Disease (CAD) Treatment (As of May 2025) The treatment of coronary artery disease (CAD) has entered an era of precision intervention through gene editing. Below is a systematic review of current gene-editing technologies applied to CAD, covering mechanis…
Innovative Strategies Combining Surgical and Gene-Editing Therapies for Coronary Heart Disease (As of May 2025) The treatment of coronary artery disease (CAD) has evolved from traditional surgical interventions to a precision medicine era. Recent advances in combining gene-editing technologies with …