mRNA

mRNA Speed: A Concise Overview mRNA Speed (or mRNA Velocity) is an analytical technique in single-cell RNA sequencing (scRNA-seq) that quantifies dynamic changes in gene expression rates and predicts future directions of cellular state transitions. Below are its key components: 1. Definition and Principle Core Concept: Compares the ratio of unspliced pre-mRNA (newly transcribed, immature RNA) to spliced mature mRNA to infer activation or suppression rates …

Velo mRNA: A Concise Overview Velo mRNA refers to mRNA Velocity, a dynamic analysis technique in single-cell RNA sequencing (scRNA-seq) that predicts future trends in gene expression, revealing directions of cell differentiation, development, or disease progression. Below are its key components: 1. Definition and Principle Core Concept: Compares the ratio of unspliced pre-mRNA (newly transcribed, immature) to spliced mature mRNA to infer activation or suppression of gene expression. Hi…

In-Depth Analysis of mRNA Velocity mRNA Velocity is an analytical method based on single-cell RNA sequencing (scRNA-seq) data. By quantifying the dynamic ratio of unspliced (pre-mRNA with introns) to spliced (mature mRNA) transcripts, it predicts future gene expression states of cells, inferring directional changes in differentiation, development, or disease progression. Its core objective is to reveal dynamic trajectories of cellular states rather than merely …