“Genedeliver” is a portmanteau of “gene delivery,” referring to gene delivery technology—the process of introducing exogenous genes into target cells through specific methods. This technology primarily encompasses the following core elements:
I. Technical Definition
Vector Function
Uses viral vectors or nanoparticles as “transport vehicles” to deliver target gene fragments into cells.
Application Scenarios
Applied in gene therapy, vaccine development, and basic research, such as CRISPR gene editing, which relies on this technology for DNA fragment delivery.
II. Key Components
Vector Types
- Viral vectors (e.g., adenovirus): High transfection efficiency but may trigger immune responses.
- Non-viral vectors (e.g., liposomes): Better safety profile but lower delivery efficiency.
Auxiliary Elements
Includes regulatory sequences such as promoters and terminators to ensure proper gene expression within cells.
III. Technological Extensions
Light-Inducible Systems
Novel delivery techniques use photosensitive compounds to control the spatiotemporal precision of gene release.
Targeted Modifications
Antibody modifications on vector surfaces enable directed delivery to specific cell types.
(Formatted for clarity and readability while maintaining technical accuracy.)