Protein Engineering in Synthetic Biology: Recent Advances and Future Prospects The convergence of synthetic biology and protein engineering is redefining biotechnology. Recent breakthroughs in protein design, optimization, and application—powered by gene editing, AI, and cross-scale engineering stra…
Applications and Innovations of Biosensors in Drug Screening Biosensors have revolutionized drug screening with their high sensitivity, real-time monitoring, and target-specific recognition. Below, we categorize key examples by technological principles and application scenarios, highlighting breakth…
The Pivotal Role of High-Precision Sensors in Synthetic Biology High-precision sensors are central to achieving dynamic control, real-time monitoring, and precision design in synthetic biology, with applications spanning fundamental research to industrial deployment. Below, we dissect their multidim…
Core Challenges in Synthetic Biology Kinetics: A Deep Dive I. Foundational Challenges in Model Construction Parameterization Challenges & Data Noise Kinetic models (e.g., ODEs, FBA) for synthetic biosystems rely heavily on experimental parameters such as enzymatic reaction rates (kcatkcat) and …
Synthetic Biology Kinetics: Theoretical Foundations for Rational Design of Biosystems Synthetic biology kinetics bridges quantitative modeling and biological system engineering, providing a mathematical framework to predict and control the dynamic behavior of engineered biological systems. This disc…
Synthetic Biology: Key Directions in Gene Manipulation I. Foundational Gene-Editing Technologies DNA Synthesis & Assembly Chemical Synthesis: Solid-phase phosphodiester bond-based synthesis produces single-stranded DNA up to 200–300 bp, enabling full gene synthesis (e.g., artificial yeast chromo…
Synaptophysin: Biological Expression and Cutting-Edge Advances I. Core Concepts of Synaptophysin Biosynthesis Definition Synaptophysin (SYP), a 38 kDa transmembrane glycoprotein belonging to the tetraspanin family, is predominantly localized on presynaptic vesicle membranes in neurons (constituting …
Synthetic Biology Hybrid (SynBioH): Designing Hybrid Biological Components and Chimeric Metabolic Pathways Engineering Enhanced Biosystems Through Cross-Species Integration and Pathway Innovation Core Principles and Design Strategies SynBioH combines elements from diverse biological systems or redes…
Synthetic Biology (SynBio): Engineering Biosystems for Medicine, Energy, and Materials Synthetic biology (SynBio) is a revolutionary discipline that merges engineering principles with biological systems to design, construct, and optimize novel organisms or biological components. By reprogramming gen…
Syn BioML: Convergence of Synthetic Biology and Machine Learning Algorithm-Driven Innovations in Drug Development, Disease Diagnosis, and Biomanufacturing Technical Framework and Core Principles Syn BioML (Synthetic Biology Machine Learning) integrates synthetic biology with machine learning to deco…