In-Depth Analysis of mRNA Velocity mRNA Velocity is an analytical method based on single-cell RNA sequencing (scRNA-seq) data. By quantifying the dynamic ratio of unspliced (pre-mRNA with introns) to spliced (mature mRNA) transcripts, it predicts future gene expression states of cells, inferring dir…
BioAI Genome: Definition and Core Principles BioAI Genome represents the intersection of Biological Artificial Intelligence (BioAI) and Genomics, focusing on the use of AI technologies to analyze, predict, design, and engineer genomic data. This field aims to achieve a deeper understanding of biolog…
RNA Tools: In-Depth Analysis and Classification (2025 Edition) RNA Tools encompasses a set of techniques and methods in molecular biology, genetic engineering, and biomedicine for studying, making, and utilizing RNA molecules. These tools range from basic research to clinical applications for RNA …
Comprehensive Guide to RNA Enzymes: Classification and Mechanisms RNA enzymes are biomacromolecules with catalytic functions, directly involved in or regulating RNA-related biochemical reactions. They are broadly classified into two categories based on molecular composition and activity: I. Ribozyme…
RNA Primer: Definition and Functional Insights An RNA primer is a short nucleic acid sequence composed of RNA nucleotides, primarily serving as a starting point for DNA synthesis during DNA replication and reverse transcription. Below is a detailed breakdown of its roles, mechanisms, and application…
In-Depth Analysis of RNA Splicing RNA splicing refers to the process in eukaryotes where precursor mRNA (pre-mRNA) undergoes removal of introns and ligation of exons to form mature mRNA. This process is critical for gene expression regulation, and aberrant splicing can lead to various diseases. Be…
In-Depth Analysis of "RNA Scan" The term "RNA Scan" is not a standardized phrase, and its meaning depends on the specific context. Below are potential interpretations across different fields: 1. Bioinformatics Tools: RNA Sequence/Structure Analysis Definition: Computational tools or workflows for sy…
Comprehensive Guide to RNAi Tools: Analysis and Classification RNAi Tools refer to a collection of experimental reagents, bioinformatics software, and database resources designed for the design, analysis, optimization, and application of RNA interference (RNAi) technology. RNAi is a gene-silencing m…
RNA Enzyme (Ribozyme): Definition and In-Depth Analysis RNA Enzyme (ribozyme) refers to a class of RNA molecules capable of catalyzing specific biochemical reactions independently of proteins. This discovery颠覆ed the traditional enzymology dogma that "all enzymes must be proteins," revealing the mult…
RNA Therapy: A Revolutionary Approach in Biomedicine RNA therapy refers to the use of RNA molecules (e.g., mRNA, siRNA, miRNA, antisense RNA) to directly intervene in disease processes. Recognized for its high efficiency and precision, this approach has emerged as a transformative technology in mo…