Gene is the fundamental unit of heredity, composed of specific DNA (or RNA) sequences that encode functional molecules (e.g., proteins or RNAs) and govern traits.
CRISPR Targeting and Precision Medicine: Revolutionizing Gene Editing to Personalized Therapies CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) technology, a groundbreaking tool in gene editing, excels at precisely targeting specific DNA sequences. This capability aligns seamlessl…
Technological Applications and Case Studies of Gene Codons Gene codons, the core units of genetic information transfer, have applications spanning basic research to industrial translation. Below, we analyze their value through codon optimization, genetic code expansion, biomedical applications, indu…
Can Synthetic Biology (SynBio) Create New Species? Synthetic Biology (SynBio), a revolutionary interdisciplinary field, aims to engineer biological systems to design or construct entirely new species not found in nature. Rapid advancements have shifted this field from theory to practice, revealing b…
Synthetic Biology (SynBio) and Artificial Life Systems: From Theory to Practice Synthetic Biology (SynBio) is revolutionizing life sciences by engineering biological systems to create or redesign life forms that transcend natural evolutionary limits. As a critical branch of SynBio, artificial life s…
Synthetic Biology (SynBio) and Cell/Gene Therapy: Technological Revolution and Clinical Applications Synthetic Biology (SynBio) is transforming cell and gene therapy (CGT) through the engineering of biological systems. By integrating biology and engineering, SynBio enables modular, programmable rede…
RNA Splicing: Biological Mechanisms and Research Advances RNA splicing, a central process in eukaryotic gene expression, ensures accurate genetic information transfer by removing introns and joining exons in precursor mRNA. This highly regulated mechanism profoundly impacts basic biology, medicine, …
RNAScan-RNA Bioinformatics Tools: A Comprehensive Overview RNA scanning tools are pivotal for decoding RNA functions, structures, and interactions across basic sequence analysis to complex functional predictions. This systematic review categorizes tools by functionality, technical principles, repres…
GenomeAPI Challenges and Optimization Strategies GenomeAPI, a critical bridge connecting vast genomic data with clinical and research applications, faces multidimensional challenges in data complexity, technical compatibility, and ethical compliance. This analysis outlines core challenges and corres…
IntronEdit Technology: Cross-Disease and Industrial Applications IntronEdit, a cutting-edge tool in gene expression regulation, overcomes the limitations of traditional gene editing (e.g., promoter optimization, UTR engineering) by precisely targeting splicing regulatory elements in intronic regions…
Genedeliver Gene Delivery Technology: Key Applications Genedeliver, centered on its DELIVER system, represents a breakthrough in gene therapy by optimizing viral vectors (e.g., AAV) for targeted and safe gene delivery. Its applications span six major therapeutic areas: 1. Targeted Musculoskeletal Th…