RNA Splicing: Biological Mechanisms and Research Advances RNA splicing, a central process in eukaryotic gene expression, ensures accurate genetic information transfer by removing introns and joining exons in precursor mRNA. This highly regulated mechanism profoundly impacts basic biology, medicine, …
RNAScan-RNA Bioinformatics Tools: A Comprehensive Overview RNA scanning tools are pivotal for decoding RNA functions, structures, and interactions across basic sequence analysis to complex functional predictions. This systematic review categorizes tools by functionality, technical principles, repres…
Watson-Crick Base Pairing in RNA Sequence-Specific Tools Watson-Crick base pairing (A-U/T and G-C) underpins RNA secondary structure stability and sequence specificity. This analysis explores how RNA tools leverage Watson-Crick interactions to achieve sequence-specific recognition and functional reg…
RNAmod and Multi-Omics Integration: From Technological Convergence to Systems Biology Revolution As an innovative tool in RNA epitranscriptomics, RNAmod (RNA Modification Analysis Platform) is redefining the boundaries of multi-omics integration through its unique multimodal data analysis capabiliti…
RNAmod: A Comprehensive Analysis Definition and Core Concept RNAmod is an integrated analysis platform designed for studying mRNA modifications (e.g., methylation, pseudouridylation), enabling the annotation, visualization, and comparison of chemical modification sites on RNA molecules. By integrati…
rnaprime.com RNA Prime: A Comprehensive Analysis Definition and Core Concept RNA Prime refers to a precision gene-editing strategy (e.g., Prime Editing) that utilizes prime editing guide RNA (pegRNA) as a "primer" or "template" to write specific edits into target DNA sequences. This approach combine…
RNAi Tools: An In-Depth Analysis RNA interference (RNAi) tools are technologies and reagents that use small RNA molecules (e.g., siRNA, shRNA) to specifically silence target gene expression. Widely applied in functional genomics, drug development, and disease therapy research, their core mechanism r…
Synth mRNA: In-Depth Analysis Synth mRNA (Synthetic mRNA) refers to artificially engineered messenger RNA molecules created via biochemical or genetic technologies. Its primary goals are to mimic or enhance natural mRNA functions while introducing novel properties—such as improved stability, control…
mRNA Speed: A Concise Overview mRNA Speed (or mRNA Velocity) is an analytical technique in single-cell RNA sequencing (scRNA-seq) that quantifies dynamic changes in gene expression rates and predicts future directions of cellular state transitions. Below are its key components: 1. Definition and P…
Velo mRNA refers to mRNA Velocity, a dynamic analysis technique in single-cell RNA sequencing (scRNA-seq) that predicts future trends in gene expression, revealing directions of cell differentiation, development, or disease progression. Below are its key components: 1. Definition and Principle Cor…